Colchicine, USP grade CAS 64-86-8

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CAS: 64-86-8

MF: C₂₂H₂₅NO₆

MW: 399.44

Product Info
Product Spec
Safety Info
Application

Product Description

Colchicine is a plant-derived alkaloid with anti-inflammatory and antimitotic properties. It disrupts microtubule polymerization by binding to tubulin and can induce apoptosis in certain cell lines. Colchicine is used in the treatment of inflammatory diseases, but due to its antimitotic properties, there is also interest in its potential as an anticancer drug.

Product Categories	Phytochemicals, Alkaloids
CAS RN	64-86-8
Alternative CAS RN	-
EC Number	200-598-5
MDL Number	-
Storage Temperature	+4°C
Shipping Temperature	Ambient
Harmonised Tariff Code	2939799090

Physical Description	White to yellow powder
Identification (IR)	To conform to standard
Specific Optical Rotation	-250.0 - -240.0 ° (c=1, alcohol)
Ethyl Acetate	≤ 8.0%
Colchicine	To pass tests
Residual Solvents	To meet requirements
Water (KF)	≤ 2.0%
Chromatographic Purity	≤ 5.0%
Assay (HPLC)	94.0 - 101.0 % (anhydrous, solvent free)
Pharmacopoeia Specification(s)	USP
Specification Version	1.0

Pictograms
Signal word	Danger
Hazard statements	H300: Fatal if swallowed H318: Causes serious eye damage H330: Fatal if inhaled H340: May cause genetic defects
Precautionary statements	P280: Wear protective gloves/protective clothing/eye protection/face protection. P301+P310: IF SWALLOWED: Immediately call a POISON CENTER/doctor/... P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P308+P313: IF exposed or concerned: Get medical advice/attention. P403+P233: Store in a well-ventilated place. Keep container tightly closed.
Supplementary EUH statements
UN Number	UN1544 - 6.1 - PG II
WGK	WGK 3
SDS Version	3.0